We Know Much about What to Do but Little about How to Do it: Experiences with a Weekly Multimicronutrient Supplementation Campaign

We know much about what to do but little about how to do it: experiences with a weekly multimicronutrient supplementation campaign.

BACKGROUND Global population growth is concentrated in urban areas, but there is little understanding of how to implement the necessary interventions to control food and nutrition insecurity. In the urban area of Peru, food insecurity is characterized mainly by micronutrient deficiencies and not by energy deficiency. OBJECTIVE To increase the effectiveness and cost-effectiveness of weekly mul...

Do We Know What We Do not Know? A Response to Celine Bonnet

Q&A: What do we know about influenza and what can we do about it?

Influenza pandemics occur when human populations are infected by a variant virus to which a population has no prior immunity. What are the crucial varying genes? The crucial genes are those encoding the two viral surface proteins hemagglutinin (H or HA) and neuraminidase (N or NA). The influenza A viruses [1] that infect mammals like us replicate principally in the epithelial cells of the airwa...

What do We Know about Natural Diets and how do We Know it?

The care and feeding of primates in captivity, be they human or other, seems based on a somewhat limited scientific basis. Observation of pathologies or limitations that have been related to nutritional or metabolic “misadventures” perhaps has been the foundation [1,2], at least in earlier times for design of “optimal diets.” That has changed from recommendations related to “four basic food gro...

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...